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Cat. No. Product Name Target Signaling Pathways
T35930 Ganglioside GM2 Mixture (sodium salt)

Ganglioside GM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane. Levels of ganglioside GM2 are elevated in the brain of patients with Sandhoff disease, as well as feline and mouse models of the disease. Ganglioside GM2 accumulates in the lysosomes of individuals with Tay-Sachs disease and GM2-activator deficiency, as well as in the CNS of patients with and animal models of mucopolysaccharide storage disorders and Niemann-Pick disease types A, C1, and C2. Gan...

化合物

Ganglioside GM2 Mixture (sodium salt)
Cat.No: T35930
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02765 GM2A Protein, Human, Recombinant (His)

GM2 ganglioside activator

Human Baculovirus Insect Cells
GM2A (GM2 ganglioside activator), is a lipid transfer protein which belongs to the ML domain family. GM2A can accommodate several single chain phospholipids and fatty acids. It also exhibits some calcium-independent phospholipase activity. GM2A binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. GM2A acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexo...

重组蛋白

GM2A Protein, Human, Recombinant (His)
Cat.No: TMPY-02765
Species: Human
Expression System: Baculovirus Insect Cells
TargetMol Loading
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